A baby boy born in Pennsylvania in June is the first birth following embryo screening using the latest gene sequencing technology designed to increase the success rate of in-vitro fertilization and reduce miscarriages

First Baby Born After Embryo Gene Sequencing to Cut Miscarriages

A baby boy born in Pennsylvania in June is the first birth following embryo screening using the latest gene sequencing technology designed to increase the success rate of in-vitro fertilization and reduce miscarriages.

Gene sequencing of embryos can identify chromosomal defects that can result in the failure of embryos to adhere to the lining of the mother’s womb, which is necessary for the fetus to receive oxygen and nutrients. Researchers at Oxford University used the technology to select healthy embryos about five days after fertilization by two couples undergoing IVF, which resulted in successful pregnancies. The study will be presented today at the European Society of Human Reproduction and Embryology’s annual meeting in London.While about 5 million babies have been born worldwide through IVF since 1978, pregnancy rates per embryo transfer in Europe was about 36 percent in 2010, according to ESHRE. Studies using older gene sequencing technology to select embryos have resulted in about a one-third increase in the chance of a healthy pregnancy and cut the miscarriage rate by about half, said Dagan Wells, lead researcher of the study.

“Next generation sequencing provides an unprecedented insight into the biology of embryos,” Wells, of Oxford’s Institute of Reproductive Sciences, said in a briefing in London on July 5.

New gene sequencing technology is more affordable than older versions, costing between 2,000 pounds ($2,977) and 3,000 pounds, Wells said. It also has an advantage over time-lapse embryo imaging, which offers limited detection of subtle chromosome abnormalities, he said.

Funding is now available to conduct a randomized trial to start by the end of the year, Wells said.

To contact the reporter on this story: Makiko Kitamura in London at mkitamura1@bloomberg.net

About bambooinnovator
Kee Koon Boon (“KB”) is the co-founder and director of HERO Investment Management which provides specialized fund management and investment advisory services to the ARCHEA Asia HERO Innovators Fund (www.heroinnovator.com), the only Asian SMID-cap tech-focused fund in the industry. KB is an internationally featured investor rooted in the principles of value investing for over a decade as a fund manager and analyst in the Asian capital markets who started his career at a boutique hedge fund in Singapore where he was with the firm since 2002 and was also part of the core investment committee in significantly outperforming the index in the 10-year-plus-old flagship Asian fund. He was also the portfolio manager for Asia-Pacific equities at Korea’s largest mutual fund company. Prior to setting up the H.E.R.O. Innovators Fund, KB was the Chief Investment Officer & CEO of a Singapore Registered Fund Management Company (RFMC) where he is responsible for listed Asian equity investments. KB had taught accounting at the Singapore Management University (SMU) as a faculty member and also pioneered the 15-week course on Accounting Fraud in Asia as an official module at SMU. KB remains grateful and honored to be invited by Singapore’s financial regulator Monetary Authority of Singapore (MAS) to present to their top management team about implementing a world’s first fact-based forward-looking fraud detection framework to bring about benefits for the capital markets in Singapore and for the public and investment community. KB also served the community in sharing his insights in writing articles about value investing and corporate governance in the media that include Business Times, Straits Times, Jakarta Post, Manual of Ideas, Investopedia, TedXWallStreet. He had also presented in top investment, banking and finance conferences in America, Italy, Sydney, Cape Town, HK, China. He has trained CEOs, entrepreneurs, CFOs, management executives in business strategy & business model innovation in Singapore, HK and China.

Leave a Reply

Fill in your details below or click an icon to log in:

WordPress.com Logo

You are commenting using your WordPress.com account. Log Out /  Change )

Google photo

You are commenting using your Google account. Log Out /  Change )

Twitter picture

You are commenting using your Twitter account. Log Out /  Change )

Facebook photo

You are commenting using your Facebook account. Log Out /  Change )

Connecting to %s

%d bloggers like this: